The Office of the Karnatak Science College, Dharwad is located on the first floor of the main building, which also houses the Chambers of the Principal, the Department of Chemistry (UG & PG) and the Department of Geology. There are eight permanent non-teaching staff members in the Office, who are aided by eleven supporting staff members (working on contract basis). The list of permanent non-teaching staff members follows.
1. Shri. Shrishail C. Hangaragi (O.S)
2. Shri. Shareef B. Rajannavar (Sr. Asst.)
3. Shri. Ambadas B. Neginahal (Sr. Asst.)
4. Shri. Mailarappa N. Sakrannavar (Sr. Asst.)
5. Shri. Atmanand Badiger (Sr. Asst.)
6. Smt. Vijayalakshmi V. Talawar (Jr. Asst.)
7. Shri. R. B. Horaginamath (Peon)